...

Ehlers-Danlos syndrome and medical cannabis

What is Ehlers-Danlos syndrome?

Ehlers-Danlos syndrome (EDS) is a group of rare genetic conditions that affect the body’s connective tissue. Connective tissue provides strength and flexibility to the skin, joints, blood vessels, and organs. People with EDS often have very flexible joints, fragile skin that bruises easily, and a higher risk of dislocations or chronic pain. The severity of symptoms can vary, with some experiencing mild joint issues and others facing more complex health challenges.

Who does Ehlers-Danlos syndrome affect?

EDS can affect men and women of any age, though many people notice symptoms during childhood or adolescence. It is an inherited condition, which means it runs in families. Those living with EDS may find everyday tasks more difficult because of frequent joint pain, fatigue, or mobility issues. In more severe cases, EDS can impact the heart and blood vessels, which may require ongoing medical care.

Standard treatment options

There is currently no cure for EDS, so treatment focuses on managing symptoms and preventing complications. Physiotherapy is often used to strengthen muscles and stabilise joints. Pain management may include over-the-counter medication, prescription drugs, or supportive devices such as braces. Regular check-ups are important for monitoring cardiovascular health, especially in certain types of EDS. Lifestyle adjustments such as avoiding high-impact activities and focusing on gentle exercise can also help reduce strain on the body.

Can medical cannabis help with Ehlers-Danlos syndrome?

Medical cannabis is being explored as an option for people with EDS who experience long-term pain or muscle spasms. Cannabinoids may help by reducing chronic pain signals, lowering inflammation, and improving sleep. For some patients, cannabis-based treatments also provide relief from anxiety that often comes with living with a long-term condition. While it is not a cure, medical cannabis may offer supportive benefits when used as part of a wider treatment plan.

If you have Ehlers-Danlos syndrome and would like to explore whether medical cannabis could help manage your symptoms, it is important to seek advice from a qualified specialist. A consultation can help you understand the potential benefits and risks and whether cannabis-based treatment is suitable for your individual needs.

CHECK ELIGIBILITY
READ MORE

Frequently Asked Questions About Arthritis Ehlers-Danlos Syndrome

What is the prevalence of EDS?

EDS is an uncommon condition that affects around one in every 5,000 individuals, while some variants of the disease are even rarer.

Is EDS inherited?

Yes, EDS can be inherited; however, some cases arise as a result of novel mutations (i.e., individuals may have no family history of the condition).

What is life like for those who have Ehlers-Danlos syndrome?

People with EDS have several challenges in their daily lives. The experience of one person with EDS may not be the same as that of another.

Some of the issues that EDS sufferers face include:

Day-to-day life: In general, people with EDS may live regular lives; nevertheless, they may experience mobility limitations. A person suffering from vascular EDS is at risk of catastrophic lethal consequences, such as ripping open a major blood vessel or organ.

Arthritis: Arthritis in EDS patients can be caused by gene mutations that alter collagen, resulting in continual joint deterioration. In this scenario, patients are recommended to avoid overextending or locking their joints, since this will result in persistent arthritis.

Breathing difficulties: A few people with kyphoscoliosis EDS may experience breathing difficulties. These can occur as a result of an aberrant spine bending both horizontally and forward.

Dental issues: gum and dental disease are common in those with the hypermobility variety of EDS.

Pain: Joint and skin issues are common in people with EDS, including easy skin rupturing, joint dislocation, and other painful symptoms.
Visual impairment: Individuals with kyphoscoliosis-type EDS are at risk for slight to serious vision impairment. These can happen if the retina is dislocated from its usual position.

Does EDS get worse with age?

The progression of Ehlers-Danlos syndrome (EDS) can vary significantly among individuals. In some cases, symptoms may stabilise or even improve over time, while in others, they may worsen.

The severity and course of EDS can be influenced by factors such as the specific type of EDS, the presence of associated conditions or complications, individual genetics, lifestyle factors, and the effectiveness of management strategies.

For some individuals with EDS, joint instability, chronic pain, and other symptoms may become more pronounced with age due to cumulative wear and tear on the body’s connective tissues.

Regular monitoring by healthcare providers and appropriate management tailored to each individual’s needs can help minimise the impact of EDS-related symptoms and complications over time.

Is CBD good for EDS?

CBD (cannabidiol) may provide potential benefits for individuals with Ehlers-Danlos Syndrome (EDS), a group of connective tissue disorders that often result in chronic pain, joint instability, and other related symptoms. While there is no cure for EDS, many people seek ways to manage the associated symptoms, particularly pain and inflammation.

Potential Benefits of CBD for EDS:

  1. Pain Relief: CBD is widely known for its analgesic (pain-relieving) properties. For those with EDS, chronic pain can be a significant concern, and CBD may help by interacting with the body’s endocannabinoid system, which plays a role in regulating pain perception.
  2. Anti-inflammatory Effects: EDS can involve inflammation in joints and tissues, contributing to discomfort. CBD has demonstrated anti-inflammatory properties, which could help reduce this inflammation and provide relief for joint-related symptoms.
  3. Muscle Relaxation: Muscle spasms and tension are common in EDS patients, particularly due to joint instability. CBD has been reported to have muscle-relaxing effects, potentially alleviating muscle tightness and discomfort.
  4. Improved Sleep: Chronic pain and discomfort often lead to sleep disturbances in people with EDS. CBD may promote better sleep quality by reducing pain and anxiety, which could help improve overall well-being.

Considerations:

  • Individual Response: While many EDS patients report positive effects from using CBD, responses can vary from person to person. It’s essential to start with a low dose and gradually increase it to find what works best for you.
  • Consult a Doctor: Given the complexities of EDS, it’s crucial to consult with a healthcare provider before trying CBD. They can help ensure it doesn’t interfere with other treatments or medications and provide personalised advice.

What are the best cannabis strains for Ehlers-Danlos syndrome (EDS)?

When it comes to cannabis strains for Ehlers-Danlos syndrome (EDS) in the UK, the focus is on managing symptoms such as chronic pain, muscle spasms, inflammation, and anxiety, which are common in patients with EDS. In the UK, only a specialist doctor can access medical cannabis, and they must prescribe it in a controlled, regulated manner. Patients with EDS often recommend the following strains for symptom management:

1. High-CBD strains for pain and inflammation

  • Benefits: CBD (cannabidiol) is known for its anti-inflammatory and analgesic properties, making it effective for reducing pain and swelling, which are common concerns for people with EDS. High-CBD strains typically offer these benefits without causing significant psychoactive effects.
  • Example: Charlotte’s Web is a popular CBD-dominant strain known for providing relief from inflammation and chronic pain while promoting a calming effect that can also help with anxiety and stress.

2. Indica-Dominant Strains for Muscle Relaxation and Sleep

  • Benefits: People commonly recommend Indica strains due to their relaxing and sedative properties. They can be effective for managing chronic pain, reducing muscle spasms, and improving sleep, all of which are important for those with EDS.
  • Example: Northern Lights is an indica strain that can offer significant pain relief and muscle relaxation, making it a beneficial option for nighttime use or for calming severe pain episodes.

3. Hybrid Strains for Balanced Symptom Relief

  • Benefits: Hybrids blend sativa and indica genetics to provide a mix of pain relief, anti-inflammatory effects, and mood enhancement. People with EDS who require symptom relief without excessive sedation during the day can benefit from these hybrids.
  • Example: Cannatonic is a popular hybrid strain known for its balanced CBD and THC content, offering effective pain relief while minimising psychoactive effects. Harlequin is another hybrid that combines CBD-rich relief with moderate amounts of THC for a well-rounded effect.

4. Sativa-Dominant Strains for Daytime Energy and Pain Management

  • Benefits: Sativa strains can offer pain relief while boosting energy and mood, making them useful for daytime use when patients need to remain alert and active. However, we advise caution, as some sativas may increase anxiety in certain individuals.
  • Example: Amnesia Haze is a sativa strain that may provide relief from pain and improve focus and energy levels, helping EDS patients manage symptoms during the day.

Can cannabis help with EDS?

Yes, cannabis may help manage symptoms of Ehlers-Danlos Syndrome (EDS). A cannabis prescription might alleviate chronic pain, reduce muscle spasms, and improve sleep for some EDS patients. However, it’s important to consult with a healthcare professional for personalised guidance.